Noromectin 1.87% Oral Paste for Horses

Name:

 Noromectin 1.87% Oral Paste for Horses

Category:

 Anthelmintics

Region:

 United Kingdom

Oral paste containing 1.87% w/w ivermectin and 2% w/w titanium dioxide.

Noromectin 1.87% Oral Paste for Horses kills the adult and some larval stages of the important internal parasites of horses. Noromectin 1.87% Oral Paste for Horses at the recommended dose rate of 200 mcg ivermectin per kg bodyweight is indicated for the treatment of the following internal parasites of horses:

Large strongyles (redworms).: adults and 4th larval (arterial) stages of Strongylus vulgaris, adults and tissue larval stages of S. edentatus and adults of S. equinus.
Adult small strongyles (redworms) including benzimidazole resistant strains: Cyathostomum catinatum, Cyathostomum pateratum, Cylicocyclus ashworthi, Cylicocyclus elongatus, Cylicocyclus insigne, Cylicocyclus leptostomum, Cylicocyclus nassatus, Cylicocyclus radiatus, Cylicostephanus asymetricus, Cylicostephanus bidentatus, Cylicostephanus calicatus, Cylicostephanus goldi, Cylicostephanus longibursatus, Cylicostephanus minutus, Cylicodontophorus bicornatus and Gyalocephalus capitatus.
Adult and immature lungworms: Dictyocaulus arnfieldi
Pinworms: Adult and immature Oxyuris equi
Ascarids: Adult and 3rd and 4th stage Parascaris equorum
Hairworms: Adult Trichostrongylus axei
Intestinal threadworms: Adult Strongyloides westeri
Neck threadworms: Microfilariae of Onchocerca spp
Oral and gastric larval stages of stomach bots: Gasterophilus spp.

Ivermectin is not effective against encysted larval stages of the small strongyles.

Noromectin 1.87% Oral Paste for Horses is administered orally at a single dose rate of 200 mcg/kg of bodyweight. One syringe division of paste should be administered per 100 kg bodyweight (based on the recommended dosage of 200 mcgg/kg). Each syringe delivers 140 mg ivermectin, sufficient to treat 700 kg of bodyweight. The tip of the syringe barrel should be inserted at the interdental space (the gap between the front and back teeth). The horse's head should be raised for a few seconds after dosing.
Horses' weight should be accurately determined for the correct use of the paste. The animal's mouth should be free of food to ensure swallowing.
For best results all horses in a yard or grazing together should be included in a regular parasite control programme and treated at the same time.

All horses should be included in a regular parasite control programme, with particular attention being paid to mares, foals and yearlings. Foals should be treated initially at 6-8 weeks of age and routine treatment repeated as appropriate. Retreatment should be carried out according to the epidemiological situation, but not less than at a 30 day interval.

Do not use the same syringe to treat more than one animal unless horses are running together or in direct contact with each other on the same premises.

As with all anthelmintics, a veterinary surgeon should establish appropriate dosing programmes and stock management to achieve adequate parasite control and reduce the likelihood of anthelmintic resistance developing.

Do not use in dogs or cats as severe adverse reactions may occur.

Do not smoke or eat while handling the product.

Wash hands after use.

Avoid eye contact.

Animals must not be slaughtered for human consumption during treatment. Horses must not be treated within 34 days of slaughter for human consumption. Do not use in mares producing milk for human consumption.

Do not store above 25ºC. Store in carton to protect from light.

This is a unidose product which should be disposed of after use.

Keep out of reach of children.

EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate surface water or ditches with product or used containers. Any unused product or waste material should be disposed of in accordance with guidance from your local waste regulation authority.

For animal treatment only.

Some horses carrying heavy infection of Onchocerca microfilariae have experienced oedema and pruritus following dosing, assumed to be the result of death of large numbers of microfilariae. These signs resolve within a few days but symptomatic treatment may be advisable.

Noromectin 1.87% Oral Paste for Horses has been formulated for use in horses only. Dogs and cats may be adversely affected by the concentration of ivermectin in the veterinary medicinal product if they are allowed to ingest spilled paste or have access to used syringes. Avermectins may not be well tolerated in all non-target species (cases of intolerance with fatal outcome are reported in dogs, especially Collies.Old English Sheepdogs and related breeds or crosses, and also in turtles/tortoises. Do not use in dogs or cats as severe adverse reactions may occur.

Do not smoke or eat while handling the product.

Wash hands after use.

Avoid eye contact.

Do not store above 25ºC. Store in carton to protect from light.

This is a unidose product which should be disposed of after use.

Keep out of reach of children.

As ivermectin is extremely dangerous for fish and aquatic life, treated animals should not have direct access to surface water and ditches during treatment.

Frequent and repeated use may lead to the development of resistance.

POM-VPS

Norbrook Laboratories Ltd

FOR ANIMAL TREATMENT ONLY

Vm 02000/4208

Some horses have experienced reactions involving cutaneous swelling and itching shortly after treatment. In most of these cases, the horses have been diagnosed as carrying heavy infections of Onchocerca microfilariae, and it is assumed the reactions are a result of the microfilariae dying in large numbers. Although the signs will resolve spontaneously in a few days, symptomatic treatment may be advisable. Consult your veterinary surgeon should these signs persist.

Horses of all ages, including young foals, pregnant mares and breeding stallions have been treated with no adverse effects on their health and fertility. Ivermectin passes readily into milk. When administering to lactating females, residues of ivermectin could be present in the maternal milk. No studies have been reported on the effect of ingestion of milk on the development of newborn foals.

Mild transitory signs (slowed pupillary light response and depression) have been seen at a higher dose of 1.8 mg/kg (9 times the recommended dose level). Other signs seen at higher doses include mydriasis, ataxia, tremors, stupor, coma and death. The less severe signs have been transitory.

Although no antidote has been identified, symptomatic therapy may be beneficial.