Alamycin LA 300

Name:

 Alamycin LA 300

Category:

 Antibiotics

Region:

 United Kingdom

A sterile aqueous solution containing Oxytetracycline Dihydrate Ph.Eur equivalent to 300 mg/ml of oxytetracycline base.

Alamycin LA 300 is a broad spectrum antibiotic indicated for use in the treatment of conditions caused by, or associated with, organisms sensitive to oxytetracycline in cattle, sheep and pigs. A wide range of Gram-positive and Gram-negative bacteria, including Bordetella bronchiseptica, Actinomyces pyogenes, Erysipelothrix rhusiopathiae, Pasteurella spp., Staphylococcus spp., and Streptococcus spp., are sensitive to oxytetracycline. Certain mycoplasma, rickettsiae, protozoa and chlamydia are also sensitive to oxytetracycline.

Alamycin LA 300 may be used in the treatment and control of a wide range of common systemic, respiratory, urinary and local infections caused by oxytetracycline sensitive organisms. Specific indications for Alamycin LA 300 would therefore include: pasteurellosis, pneumonia, atrophic rhinitis, erysipelas, joint-ill/navel ill, summer mastitis in cows, ovine keratoconjunctivitis (pink-eye) and the control of enzootic abortion in sheep.

Alamycin LA 300 is specifically formulated to provide a prolonged action, resulting in sustained antibacterial activity. Following intramuscular administration effective blood levels persist for 3 - 4 days at a dose rate of 20 mg/kg and for 5 - 6 days at a dose rate of 30 mg/kg. Maximum blood levels are achieved between 4 - 6 hours following administration making Alamycin LA 300 suitable for the treatment of acute infections.

Administer by deep intramuscular injection to cattle, sheep and pigs for the treatment and control of conditions caused by organisms sensitive to the action of oxytetracycline.

Alamycin LA 300 can be administered at the standard dose of 20 mg/kg in order to obtain 3 to 4 days duration of activity or at the high dose of 30 mg/kg for prolonged duration of activity (i.e. activity maintained for 5 to 6 days). Use aseptic injection technique.

Maximum recommended dosage at one site:

Do not dilute Alamycin LA 300.

Although Alamycin LA 300 is well tolerated, occasionally a slight local reaction of a transient nature may be observed.

The use of tetracyclines during the period of tooth and bone development, including late pregnancy, may lead to discolouration.

Oxytetracycline therapy does not completely eliminate chlamydial infection in a flock.

If concurrent treatment is administered use a separate injection site.

Avoid accidental self-injection.
Wash hands after use.
In case of contact with eyes or skin wash immediately with water as irritation may occur.

Meat: Animals must not be slaughtered for human consumption during treatment.

20 mg/kg dose: Cattle and sheep may be slaughtered for human consumption only after 28 days from the last treatment. Pigs may be slaughtered for human consumption only after 14 days from the last treatment.

30 mg/kg dose: Cattle may be slaughtered for human consumption only after 35 days from the last treatment. Sheep and pigs may be slaughtered for human consumption only after 28 days from the last treatment.

Milk: Milk for human consumption must not be taken during treatment. Milk for human consumption may be taken from cows only after 10 days from the last treatment. Milk for human consumption may be taken from ewes only after 8 days from the last treatment.

Dispose of any unused product, unused and empty containers in accordance with guidance from your local waste regulation authority.

Do not store above 25C. Protect from light. Following withdrawal of the first dose use the product within 28 days. Discard unused material. Keep out of reach of children.

POM-V

Multi-dose vials of 100ml.

Norbrook Laboratories Ltd

Vm 02000/4113

If stored as directed Alamycin LA 300 can be expected to retain its potency for 2 years from the manufacturing date. When the vial has been broached and the contents exposed to air, the solution may darken but the potency will be unchanged.