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Date: Tuesday 06 January 
 

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Bovaclox DC Xtra


 

Name:

 Bovaclox DC Xtra

 

Category:

 Intramammaries

 

Region:

 United Kingdom

 

 

 

Presentation:

 

Bovaclox DC Xtra is an off-white stable dry cow intramammary suspension, dry cow, prepared under sterile conditions. Each single dose 5.4 g syringe contains:

Cloxacillin (as benzathine salt) 600 mg
Ampicillin (as ampicillin trihydrate Ph.Eur.) 300 mg
in a long acting base.

Ampicillin and cloxacillin are semi-synthetic penicillins derived from 6-aminopenicillanic acid.

     

Product Uses:

 

Bovaclox DC Xtra is formulated for use in the dairy cow at the point of drying off, that is, immediately after the last milking of the lactation, in order to treat existing mastitis and to provide protection against further infections during the dry period.

Bovaclox DC Xtra is a useful aid in reducing the incidence of summer mastitis in heifers and dry cows at risk.

Bovaclox DC Xtra is active against both Gram-positive and Gram-negative organisms which are associated with mastitis and is effective against Streptococcus agalactiae and other Streptococcus species, penicillin resistant and sensitive Staphylococci, Corynebacterium species, Escherichia coli and other susceptible Gram-negative bacteria.

Cloxacillin benzathine and ampicillin trihydrate in a long-acting base maintain effective antibacterial levels in the dry cow udder for up to 10 weeks and are non-irritant to udder tissue.

     

Dosage Admin:

 

Dry Off Therapy: After the final milking of a lactation, clean and disinfect the teats and introduce the contents of one syringe into each quarter via the teat canal. Avoid contamination of syringe nozzle.

 

     

Contra Indications:

 

Do not use on cows which have a very short dry period. Must not be used in lactating cows. Not intended for use within 49 days of calving. Milk for human consumption may only be taken from 156 hours after calving. Should a cow calve earlier than 49 days after the last treatment, milk for human consumption may only be taken from 49 days plus 156 hours after the last treatment.

Animals must not be slaughtered for human consumption during treatment. Cattle may be slaughtered for human consumption only after 28 days from the last treatment.

In cows suffering from hypocalcaemia it may be necessary to withhold milk for a longer period, until the levels of antibiotic are below the maximum acceptable residue levels i.e., 0.03 mcg/ml for cloxacillin and 0.004 mcg/ml for ampicillin.

When infusing heifers it is important that the syringe nozzle is not introduced into the teat. The recommended procedure is as follows:

The animal(s) should be properly restrained. The teats are cleaned and disinfected. The teat orifice is located and the nozzle of the syringe placed against it but NOT inserted. When the syringe plunger is depressed the antibiotic passes easily through the teat into the udder.

     

Operator Warnings:

 

Protective gloves should always be worn when infusing heifers, to avoid skin contact with the product.

Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross-reactions to cephalosporins and vice versa. Allergic reaction to these substances may occasionally be serious.

Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations.

Handle this product with great care to avoid exposure taking all recommended precautions.

If you develop symptoms following exposure, such as a skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty in breathing are more serious symptoms and require urgent medical attention.

Wash hands after use.

     

Product Disposal:

 

Dispose of any unused product and empty containers in accordance with guidance from you local waste regulation authority.

     

Pharmaceutical Precautions:

 

Store below 25C. Keep out of reach of children. The syringe may only be used once. Part-used syringes must be discarded.

     

Legal Category:

 

POM - V

     

Packaging Quantities:

 

Cartons of 24 and 120 syringes, each syringe containing 600mg cloxacillin as the benzathine salt and 300mg ampicillin as the trihydrate.

     

Manufacturer Ident:

 

Norbrook Laboratories Ltd

     

Version Info:

 

Vm 02000/4111

     

Further Info:

 

Bovaclox DC Xtra must not be used in the treatment of lactating cows.

     
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Norbrook Laboratories Ltd. Station Works, Newry, Co. Down. BT35 6JP Northern Ireland Tel: +44 (0)28 3026 4435 Fax: +44 (0)28 3026 1721
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